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KMID : 0358320100510100694
Korean Journal of Urology
2010 Volume.51 No. 10 p.694 ~ p.699
Clinical and Urodynamic Significance of Morphological Differences in Intravesical Prostatic Protrusion
Lee Seung-Wook

Cho Jeong-Man
Kang Jung-Yoon
YooTag-Keun
Abstract
PurposeThe objectives of this study were to evaluate whether morphologic differences correlated with urodynamic and clinical characteristics in patients with benign prostatic hyperplasia (BPH) with intravesical prostatic protrusion (IPP) of trilobar or bilobar adenoma.

Materials and MethodsBetween January 2008 and June 2009, 72 male patients who had undergone transurethral resection (TUR) owing to BPH with IPP were included in this study. They underwent preoperative urodynamic studies, the International Prostate Symptom Score (IPSS)/quality of life (QoL), maximal flow rate (Qmax), post-voiding residual urine volume (PVR), transrectal ultrasonography (TRUS), and serum prostate-specific antigen (PSA) measurement. The patients were classified into 2 groups (the trilobar and bilobar adenoma groups) on the basis of video findings during the TUR operation.

ResultsThe trilobar and bilobar adenoma groups consisted of 37 patients and 35 patients, respectively. The Mean¡¾SD IPP, prostate volume (PV), and transition zone volume of the trilobar and bilobar adenoma groups were 11.8¡¾5.2 mm and 9.0¡¾3.8 mm (p=0.014), 81.1¡¾25.8 g and 59.3¡¾22.5 g (p<0.001), and 49.6¡¾20.6 g and 34.8¡¾19.4 g (p=0.003), respectively. The Mean¡¾SD PSA, bladder contractility index (BCI), and bladder outlet obstruction index (BOOI) were 4.6¡¾2.5 ng/ml and 3.5¡¾1.7 ng/ml (p=0.042), 119.8¡¾33.4 and 87.7¡¾24.4 (p<0.001), and 62.6¡¾29.5 and 44.6¡¾20.4 (p=0.005), respectively. There were no significant differences in IPSS/QoL, Qmax, PVR, acute urinary retention, or detrusor overactivity in the 2 groups.

Conclusions IPP has two morphologic types of trilobar or bilobar enlargement. The PV, BOOI, and BCI were significantly smaller in the bilobar adenoma group than in the trilobar adenoma group.
KEYWORD
Prostatic hyperplasia, Ultrasonography, Urodynamics
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